KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATF4
All Species:
26.36
Human Site:
S172
Identified Species:
58
UniProt:
P18848
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18848
NP_001666.2
351
38590
S172
L
S
P
G
V
L
S
S
T
P
D
H
S
F
S
Chimpanzee
Pan troglodytes
XP_001165876
351
38562
S172
L
S
S
G
V
L
S
S
T
P
D
H
S
F
S
Rhesus Macaque
Macaca mulatta
XP_001099190
351
38511
S172
L
S
P
G
V
L
S
S
T
P
D
H
S
F
S
Dog
Lupus familis
XP_531731
350
38528
S172
L
S
P
G
A
L
S
S
T
P
D
H
S
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q06507
349
38337
S171
C
S
P
G
V
L
S
S
T
P
E
H
S
F
S
Rat
Rattus norvegicus
Q9ES19
347
38133
S170
C
S
P
G
F
L
S
S
T
P
D
H
S
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519185
358
39350
P174
P
E
A
L
T
S
T
P
D
H
S
F
S
L
E
Chicken
Gallus gallus
NP_990211
354
38972
S172
L
S
P
G
S
L
T
S
V
P
D
H
S
F
S
Frog
Xenopus laevis
NP_001083212
336
36859
S168
S
F
I
L
D
L
G
S
E
V
D
V
A
E
D
Zebra Danio
Brachydanio rerio
Q6NW59
339
36586
A174
V
P
S
P
P
E
E
A
P
Q
D
E
H
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393709
357
41262
L168
D
T
Q
L
L
V
T
L
Q
P
V
Q
P
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.2
90.5
N.A.
86
87.1
N.A.
71.2
64.4
54.1
32.7
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
100
99.1
98.5
93.1
N.A.
90.5
91.1
N.A.
81.5
78.8
66.6
48.4
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
86.6
86.6
N.A.
6.6
80
20
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
86.6
N.A.
13.3
86.6
26.6
20
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
10
0
0
0
0
10
0
0
% A
% Cys:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
10
0
73
0
0
0
10
% D
% Glu:
0
10
0
0
0
10
10
0
10
0
10
10
0
10
19
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
10
0
64
0
% F
% Gly:
0
0
0
64
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
64
10
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
46
0
0
28
10
73
0
10
0
0
0
0
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
55
10
10
0
0
10
10
73
0
0
10
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
10
10
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
64
19
0
10
10
55
73
0
0
10
0
73
0
64
% S
% Thr:
0
10
0
0
10
0
28
0
55
0
0
0
0
10
0
% T
% Val:
10
0
0
0
37
10
0
0
10
10
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _